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Back to the experimentTHE EVIDENCE BEHIND THE EXPERIENCE

A little less can do a lot: sources & model

Tip a virtual platform under a real 3D ankle. Discover why one muscle gets more drive while its partner gets less, follow the spinal circuit, and change one connection to see the difference.

Scientific review · independent subject review pending

The source and model records are available for inspection. No external scientific reviewer has signed off yet.

reflexes-1 · content 1 · setup format 1

What supports the explanation?

Human ankle pathways support reciprocal Ia inhibition

Crone et al. studied 60 humans using conditioned soleus and tibialis-anterior H reflexes. The extra central delay was inferred under a symmetry assumption; our drive gains are not taken from their data.

Crone et al. · Journal of Physiology, 1987

An inhibitory interneuron explains the selected reciprocal branch

Original human forearm conditioning experiments; corroborating pathway evidence, not ankle-specific simulation constants.

Day et al. · Journal of Physiology, 1984

Human muscle spindle responses depend on mechanical conditions

Original recordings from human muscle spindle afferents during vibration, length and movement conditions. The lesson does not reproduce their firing rates.

Burke et al. · human spindle recordings, 1976

Some fast feedback involves motor cortex

Primary human and rhesus-monkey experiments on multijoint feedback control. Distinguish these experimental tasks from the modeled ankle.

Pruszynski et al. · Nature, 2011

Crossed effects differ during standing and walking

Human conditioned soleus H-reflex measurements. The 100–130 ms intervals are between conditioning and test stimuli, not natural movement onset delays.

Suzuki et al. · Experimental Brain Research, 2014

Walking research separates measurements from estimated neural activity

Gervasio et al. 2017, PLOS ONE 12(1):e0168557. Complete Figure 3 documents the setup and is reused under CC BY 4.0. This paper is separate from Suzuki’s standing/walking comparison.

Gervasio et al. · PLOS ONE, 2017

Inhibition has a long experimental history in coordination

Sherrington’s own 1932 Nobel lecture. Historical animal experiments are not direct human measurements or the origin of our authored numerical gains.

Sherrington · original Nobel lecture, 1932

Dorsal and ventral roots have distinct anatomical identities

FIPAT Terminologia Neuroanatomica. Terminology guides the detached functional diagram; it does not validate authored geometry.

FIPAT · Terminologia Neuroanatomica

The 3D anatomy is from the dataset owner’s source meshes

BodyParts3D, © The Database Center for Life Science licensed under CC Attribution 4.0 International. Current owner license updated February 2025; source selections and changes are recorded in the manifest.

DBCLS · BodyParts3D license and attribution

Pain is not inferred solely from sensory-neuron activity

IASP’s definition distinguishes personal pain experience from nociception. No pain prediction or self-test is offered.

IASP · revised definition of pain

What this model assumes

  1. Anatomy comes from selected BodyParts3D 4.0 right-sided muscles, tendon and bones. The platform, spindle locator, articulation and functional circuit are authored illustrations, not an observed reflex in motion.
  2. The ankle uses an approximate single pivot and a smooth deformation of selected soft tissues. The platform prescribes the foot pose. Outputs do not solve joint torque, balance, muscle force, tendon strain or realistic spindle dynamics.
  3. Model drive is a normalized teaching quantity. The gains and playback stages are authored; there are no physiological milliseconds, Hz, EMG or force units attached to them. Removing inhibition is a counterfactual circuit comparison, not a diagnosis.
  4. The circuit selects one Ia stretch-response branch. It omits many neurons, inputs, presynaptic regulation, descending influences and task-dependent dynamics. Inhibition is shown at the opposing motor pool.
  5. Withdrawal and crossed-response evidence concerns different inputs and experiments. The standing/walking comparison is qualitative evidence about an H reflex, not a gait simulator.
  6. The scientific figure is a static diagram of a research setup. It is not a photograph, a result graph or a home experiment. Source geometry and figure attribution are downloadable. Independent subject and learner review of the finished lesson remains pending.
  7. A sensory route and a motor route: Sensory fibers enter through dorsal, or posterior, roots. The sensory cell body is in a dorsal-root ganglion outside the cord; it is not an extra compulsory relay between two neurons. Motor axons leave through ventral, or anterior, roots. Our detached diagram has dorsal at the top and ventral at the bottom. It does not align spinal segments with vertebral levels.
  8. Count central synapses carefully: The selected direct Ia afferent-to-motor-neuron branch has one central synapse. The reciprocal branch includes an inhibitory interneuron, giving two central synapses. Both include additional events elsewhere, including the neuromuscular junction. Neither count is a complete description of every stretch-related response.
  9. The small model we actually calculate: Let u be authored stretch input from 0 to 1, b background drive, and g be 1 with the inhibitory connection or 0 with it removed. At the completed teaching stage: calf drive = clamp(b + 0.5u); opposing drive = clamp(b − 0.3gu). Clamp keeps outputs in [0,1]. The gains 0.5 and 0.3 are chosen for a readable comparison. They are not fitted nerve, EMG, force or movement measurements. During playback we reveal the result in stages, on an illustrative clock.
  10. An extra relay is not the whole response time: Crone and colleagues studied reciprocal ankle pathways in 60 humans in 1987 using conditioned H reflexes. Assuming symmetric central connections, they inferred about 1 ms of additional central delay relative to monosynaptic Ia excitation. That comparison does not measure the whole time from an everyday stimulus to movement, and it says nothing about when someone becomes aware of pain.
  11. Fast feedback can include the cortex: Pruszynski and colleagues combined human and rhesus-monkey experiments in 2011 to investigate rapid multijoint feedback and motor-cortex contributions. This evidence expands the simple spinal picture. It does not make our ankle illustration a model of every arm response or assign one delay to all people.
  12. The other side changes with the task: Suzuki and colleagues compared crossed cutaneous effects on a soleus H reflex in humans. They found facilitation while standing at selected conditioning-to-test intervals, but suppression during early stance in walking. The measured endpoint was electrically probed reflex excitability, not whole-leg force. Gervasio and colleagues separately studied crossed responses during walking and distinguished measured data from modeled afferent activity.
  13. Reflex measures are not a pain meter: Nociception concerns neural processing of potentially tissue-damaging input. Pain is a personal sensory and emotional experience. Experimental reflex measures and reported pain can dissociate. This lesson neither assigns a pain score nor tests a learner’s neurological function.

What has been checked

Analytical reference cases, conservation or transition invariants, finite drawing commands, bounded setup parsing, discovery and route integrity are checked automatically. These checks do not establish anatomical fidelity, learner outcomes or browser/device compatibility. Independent subject review, learner trials, comprehensive accessibility review and browser video encoding checks remain pending.

Each source supports the associated claim. Sources do not certify this implementation or its visuals.

About the cover illustration

Source-derived right ankle anatomy from BodyParts3D © DBCLS, CC BY 4.0. Selected muscles, Achilles tendon and bones. Original source geometry; authored colors and articulation in the lesson.

Our review process